Ibuprofen and ibuprofen/paracetamol combination were more effective than normal- or high-dose paracetamol in reducing children’s pain and distress following extraction of teeth. Dental implants have become a predictable and widely used treatment for restoration of oral function. Both paracetamol and ibuprofen are commonly used for the relief of pain following the surgical removal of lower wisdom teeth. In 2010, a new painkiller (marketed as Nuromol) containing paracetamol and ibuprofen in the same tablet was licensed for use in the United Kingdom. This paper compares the beneficial and harmful effects of paracetamol, ibuprofen and the novel combination of both in a single tablet for pain relief following the surgical removal of lower wisdom. The combination of paracetamol and ibuprofen has been found to be efficacious in a variety of acute pain states, including postoperative pain, dysmenorrhoea and musculoskeletal pain. 8-15 A Cochrane review assessed the efficacy of single-dose paracetamol plus ibuprofen in a variety of dose combinations after wisdom tooth removal. 8 Wisdom tooth pain is usually down to the gum around it or flap of gum over it being swollen and sometimes infected. You may need a short course of antibiotics. Xx You may need a short course of antibiotics. Review question. This review, carried out by the Cochrane Oral Health Group, seeks to compare the effectiveness of two commonly used painkillers, paracetamol and ibuprofen and the combination of both in a single tablet in the relief of pain following surgical removal of lower wisdom teeth. Painkillers and anti-inflammatories (e.g. paracetamol, aspirin and ibuprofen) can help bring pain relief… Pain-killers for Relief of Wisdom Tooth Pain A variety of over-the-counter painkillers can be useful. Both paracetamol and ibuprofen are commonly used analgesics for the relief of pain following the surgical removal of lower wisdom teeth (third molars). In 2010, a novel analgesic (marketed as Nuromol) containing both paracetamol and ibuprofen in the same tablet was launched in the United Kingdom.